Validating an Animal Model of PTSD Through Open Field Behavior

dc.contributor.advisor	Malin, David
dc.contributor.committeeMember	Ward, Christopher
dc.creator	Davis, Tasha
dc.creator.orcid	0000-0002-5795-0985
dc.date.accessioned	2018-03-13T22:13:56Z
dc.date.available	2018-03-13T22:13:56Z
dc.date.created	2017-12
dc.date.issued	2017-12-21
dc.date.submitted	December 2017
dc.date.updated	2018-03-13T22:13:56Z
dc.description.abstract	Post-traumatic stress disorder (PTSD) is a prevalent anxiety disorder that affects people all over the world. Animal models are often used in clinical research to study human disorders; rats and humans share some similar genetic and biological traits. The open field model is a common paradigm for testing locomotor activity and anxiety related behaviors in rats. This study looks at the effect of anxiety-like behaviors in an open field on a rodent model of PTSD. Anxiety-like behaviors were examined after exposure to either restraint stress and predator odor or no restraint stress and no predator odor. Significant differences were found in three of the open field measures assessed in attempts to validate an animal model of PTSD through open field behavior.
dc.format.mimetype	application/pdf
dc.identifier.uri	http://hdl.handle.net/10657.1/824
dc.subject.lcsh	Post-traumatic stress disorder
dc.subject.lcsh	Animal behavior
dc.title	Validating an Animal Model of PTSD Through Open Field Behavior
dc.type	Thesis
dc.type.material	text
thesis.degree.grantor	University of Houston - Clear Lake
thesis.degree.level	Masters
thesis.degree.name	Master of Science

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