Institutional Repository @ UHCL: Recent submissions
Now showing items 1-20 of 2058
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Elementary teachers' self-efficacy beliefs related to teaching students displaying externalizing and internalizing behaviors
(2019-08-08)The purpose of this quantitative study was to determine if there is a relationship between teacher-reported self-efficacy beliefs when working with students displaying externalizing and internalizing behaviors and the ... -
pH Neutralization Protects Against Reduction in Replicative Lifespan Following Chronological Aging in Yeast
(Cell Cycle, 2012)Chronological and replicative aging have been studied in yeast as alternative paradigms for post-mitotic and mitotic aging, respectively. It has been known for more than a decade that cells of the S288C background aged ... -
Quantitative determination of isopentenyl diphosphate in cultured mammalian cells
(Analytical Biochemistry, 2012)Isopentenyl diphosphate (IPP), an intermediate of the isoprenoid biosynthetic pathway (IBP), has several important biological functions, yet a method to determine its basal level has not been described. Here, we describe ... -
Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae
(Experimental Gerontology, 2012)Chronological aging of budding yeast cells result in a reduction in a subsequent replicative life span through unknown mechanisms. Here, we show that dietary restrictions during chronological aging delays the reduction ... -
Yeast Replicative Aging; A Paradigm for Defining Conserved Longevity Interventions
(FEMS Yeast Research, 2014)The finite replicative life span of budding yeast mother cells was demonstrated as early as 1959, but the idea that budding yeast could be used to model aging of multicellular eukaryotes did not enter the scientific ... -
mTOR Inhibition by Rapamycin Alleviates Mitochondrial Disease in the Ndufs4-Mouse Model of Leigh Syndrome
(Science, 2013)Mitochondrial dysfunction contributes to numerous health problems, including neurological and muscular degeneration, cardiomyopathies, cancer, diabetes, and pathologies of aging. Severe mitochondrial defects can result ... -
End-of-lfe Cell Cycle Arrest Contributes to Stochasticity of Yeast Replicative Aging
(FEMS Yeast Research, 2013)There is growing evidence that stochastic events play an important role in determining individual longevity. Studies in model organisms have demonstrated that genetically identical populations maintained under apparently ... -
Molecular Mechanisms Underlying Genotype-dependent Responses to Dietary Restrictions
(Aging Cell, 2013)Dietary restriction (DR) increases lifespan and attenuates age-related phenotypes in many organisms; however, the effects of DR on longevity of individuals in genetically heterogeneous populations is not well characterized. ... -
Development of an Effective Organizational Performance Instrument to Facilitate Post-Secondary Institutional Change: A Variation on Likert's Management Systems 1-5
(2020-10-13)This study stemmed from the need to develop an instrument for assessing the characteristics of an organization in terms of internal consistency of leadership behavior, interaction-influences between colleagues, communication ... -
Buffering the pH of the Culture Medium does not Extend Yeast Replicative Lifespan
(F1000 Research, 2013)During chronological aging of the budding yeast cells, the culture medium can become acidified and this acidification limits cell survival. As a consequence, buffering the culture medium to pH 6 significantly extends ... -
Nar1 Deficiency Results in Shortened Lifespan and Sensitivity to Paraquat that is Rescued by Increased Expression of Mitochondrial Superoxide Dismutase
(Mech Ageing Dev, 2014)Saccaromyces cerevisiae Nar lp is an essential Fe/S protein that exhibits striking similarity to bacterial iron-only hydogenases. Nar1p is required for the maturation of cytosolic and nuclear, but not of mitochondrial ... -
FPGA Acceleration on Multilayer Perceptron (MLP) Neural Network for Handwritten Digit Recognition
(2020-05-13)This dissertation presents a hardware implementation of a Multi-Layer Perceptron (MLP) network used for the purpose of low-latency, high-accuracy digit recognition. The accuracy of various network designs was compared in ... -
Classification of Positive and Negative Stimuli Using EEG Data Functional Connectivity and Machine Learning
(2019-12-06)Electroencephalography (EEG) provides electrical measures of brain activity by monitoring voltage fluctuations of the collective neural activity in different parts on the cortex of the brain. Recently, there have been ... -
A Framework for Planetary Resource Classifications to Further Sustainability in Space Exploration Missions
(2020-12-21)The long-term impacts and overall sustainability of space exploration missions in the space environment were often unknown in past space missions. Historically, the space exploration vision of various space-faring agents ... -
The Impact of Teacher Perceptions About Student Socioeconomic Status on Grading Practices
(2020-12-04)The current study investigated if teachers’ perceptions of student socioeconomic status (SES) resulted in higher grades for high-SES students compared to low-SES students. Sixty-nine participants read one of two nearly ... -
The Role of Remorse and Gender in Juror Decision Making for Capital Punishment
(2020-12-03)While defendants are expected to show remorse for committing a crime (Sundby, 1998) and remorse is particularly important during the sentencing phase of a trial (Zhong et al., 2014), there is little systematic evidence to ... -
The Effects of Pimavanserin on Corticosterone Levels in a Rodent Model of Posttraumatic Stress Disorder
(2020-12-07)PTSD can affect individuals that have experienced or witnessed a traumatic event, resulting in numerous physical and psychiatric symptoms. Selective serotonin reuptake inhibitors (SSRIs) and behavior therapy are often ... -
Exploratory Analysis of Delay Discounting and Cognitive-Affective Regulation Measures in Cocaine Users
(2020-12-04)Research investigating addiction across populations suggests that identifying high-risk behavioral factors within a population may help identify key areas to target during treatment. Delay discounting, the measure of the ... -
Exploiting Area-Speed-Power Tradeoff of FPGA Designs on Multilayer Perceptron (MLP) Neural Network
(2020-12-21)This dissertation presents four Field Programmable Gate Array (FPGA) design architectures for handwritten digit recognition, in order to improve hardware efficiency in terms of resources, power, and speed of the neuromorphic ... -
Tradeoff FPGA Cost of Sobel Implementation Using Approximate Designs
(2020-12-21)This dissertation proposes a scalable algorithm for tuning the tradeoff of space, energy, and quality for the implementation on Field-Programmable Gate Array (FPGA). First, an approximate design library including exact and ...
