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Nar1 Deficiency Results in Shortened Lifespan and Sensitivity to Paraquat that is Rescued by Increased Expression of Mitochondrial Superoxide Dismutase
(Mech Ageing Dev, 2014)
Saccaromyces cerevisiae Nar lp is an essential Fe/S protein that exhibits striking similarity to bacterial iron-only hydogenases. Nar1p is required for the maturation of cytosolic and nuclear, but not of mitochondrial ...
Yeast Replicative Aging; A Paradigm for Defining Conserved Longevity Interventions
(FEMS Yeast Research, 2014)
The finite replicative life span of budding yeast mother cells was demonstrated as early as 1959, but the idea that budding yeast could be used to model aging of multicellular eukaryotes did not enter the scientific ...