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dc.contributor.advisorMalin, David
dc.creatorDavis, Tasha
dc.date.accessioned2018-03-13T22:13:56Z
dc.date.available2018-03-13T22:13:56Z
dc.date.created2017-12
dc.date.issued2017-12-21
dc.date.submittedDecember 2017
dc.identifier.urihttp://hdl.handle.net/10657.1/824
dc.description.abstractPost-traumatic stress disorder (PTSD) is a prevalent anxiety disorder that affects people all over the world. Animal models are often used in clinical research to study human disorders; rats and humans share some similar genetic and biological traits. The open field model is a common paradigm for testing locomotor activity and anxiety related behaviors in rats. This study looks at the effect of anxiety-like behaviors in an open field on a rodent model of PTSD. Anxiety-like behaviors were examined after exposure to either restraint stress and predator odor or no restraint stress and no predator odor. Significant differences were found in three of the open field measures assessed in attempts to validate an animal model of PTSD through open field behavior.
dc.format.mimetypeapplication/pdf
dc.subject.lcshPost-traumatic stress disorder
dc.subject.lcshAnimal behavior
dc.titleValidating an Animal Model of PTSD Through Open Field Behavior
dc.typeThesis
dc.date.updated2018-03-13T22:13:56Z
thesis.degree.grantorUniversity of Houston - Clear Lake
thesis.degree.levelMasters
thesis.degree.nameMaster of Science
dc.contributor.committeeMemberWard, Christopher
dc.type.materialtext
dc.creator.orcid0000-0002-5795-0985


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