Browsing Colleges by Subject "Aging; DNA damage; Geroscience; Iron-sulfur clusters; Lysosomal acidity; Vacuolar acidity; Yeast replicative lifespan."

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Loss of Vacuolar Acidity Results in Iron Sulfur Cluster Defects and Divergent Homeostatic Responses During Aging in Saccharomyces Cerevisiae

Wasko, Brian (GeroScience, 2020)

The loss of vacuolar/lysosomal acidity is an early event during aging that has been linked to mitochondrial dysfunction. However, it is unclear how loss of vacuolar acidity results in age-related dysfunction. Through ...