Now showing items 1-20 of 20

      : yeast longevity replication stress chronological lifespan replicative lifespan [1]
      Aging / genetics* Aging / metabolism Basic-Leucine Zipper Transcription Factors / genetics Basic-Leucine Zipper Transcription Factors / metabolism Blotting, Western Endoplasmic Reticulum Stress Longevity / genetics* Mannosyltransferases / genetics* Mannosyltransferases / metabolism Membrane Glycoproteins / genetics Membrane Glycoproteins / metabolism Polymerase Chain Reaction Protein-Serine-Threonine Kinases / genetics Protein-Serine-Threonine Kinases / metabolism Repressor Proteins / genetics Repressor Proteins / metabolism Saccharomyces cerevisiae / genetics* Saccharomyces cerevisiae / metabolism Saccharomyces cerevisiae Proteins / genetics Saccharomyces cerevisiae Proteins / metabolism Unfolded Protein Response* [1]
      aging, aneuploidy, BUL1, protein trafficking, replicative lifespan [1]
      aging; dietary restriction; longevity; mitochondria; mitochondrial unfolded protein response; replicative lifespan; yeast. [1]
      Aging; DNA damage; Geroscience; Iron-sulfur clusters; Lysosomal acidity; Vacuolar acidity; Yeast replicative lifespan. [1]
      Animals, Brain/drug effects, Brain/enzymology, Brain/pathology, Disease Models, Animal Electron Transport Complex I/genetics, Electron Transport Complex I/metabolism, Glycolysis/drug effects, Leigh Disease/drug therapy, Leigh Disease/genetics, Leigh Disease/pathology, Mechanistic Target of Rapamycin Complex 1, Mice Mice, Knockout Mice, Mutant Strains Mitochondria/drug effects, Mitochondria/enzymology, Mitochondrial Diseases/drug therapy, Mitochondrial Diseases/genetics, Mitochondrial Diseases/pathology, Molecular Targeted Therapy, Multiprotein Complexes/antagonists & inhibitors, Neuroprotective Agents/therapeutic use, Sirolimus/therapeutic use, TOR Serine-Threonine Kinases/antagonists & inhibitors [1]
      Biomarkers, Genetics, Proteins [1]
      BioProject, Gene, Gene links, GEO DataSets, GEO Profiles, MedGen, PubMed, SRA Taxonomy [1]
      Caenorhabditis elegans; caloric restriction; calorie restriction; replicative life span; target of rapamycin; yeast. [1]
      CAN1, gene expression, aging, translation efficiency, protein abundance, [1]
      Cell Cycle Checkpoints, Microbial Viability, Stochastic Processes, Yeasts/physiology [1]
      chronological lifespan, replicative lifespan, caloric restriction, calorie restriction, dietary restriction, glucose, mitochondria [1]
      culture medium, pH, replicative aging, buffering [1]
      Farnesyltranstransferase / metabolism Hemiterpenes / analysis* Hemiterpenes / metabolism Humans K562 Cells MCF-7 Cells Organophosphorus Compounds / analysis* Organophosphorus Compounds / metabolism Polyisoprenyl Phosphates / metabolism Reproducibility of Results Terpenes / metabolism [1]
      Lifespan; Mitochondrial superoxide dismutase; Nar1 [1]
      Mitochondria, RNA interference, Aging, Caenorhabditis elegans, Gene expression, MAPK signaling cascades, Oxidation-reduction reactions, Oxidative stress [1]
      mitochondrial iron–sulfur protein, aging, Rip1. isp-1. complex III [1]
      Mutation, Cancer, MMR, Diploid strain, mutation burden [1]
      Rip1; aging; complex III; iron-sulfur protein; isp-1; tether [1]
      S. cerevisiae, lifespan, aging, los1, tRNA transport, Rad53, mTOR [1]